持续近两个多月的新型冠状病毒感染的肺炎疫情牵动着每一个人的心，为了打赢这场疫情防控狙击战，搞清致病机理，研发抗病毒药物和疫苗刻不容缓。Jena bioscience品牌有丰富的抗病毒核苷酸/核苷酸类似物，助力抗病毒药物研发。
抗病毒核苷及核苷酸类似物主要有:
|
货号 |
品名 |
规格 |
|
NU-1605S |
3TCMP |
10 μl (10 mM) |
|
NU-1605L |
3TCMP |
5 x 10 μl (10 mM) |
|
NU-1606S |
3TCTP |
5 μl (10 mM) |
|
NU-1606L |
3TCTP |
5 x 5 μl (10 mM) |
|
NU-1603S |
d4TMP |
20 μl (10 mM) |
|
NU-1603L |
d4TMP |
5 x 20 μl (10 mM) |
|
NU-1601S |
AzTMP |
20 μl (10 mM) |
|
NU-1601L |
AzTMP |
5 x 20 μl (10 mM) |
|
NU-989S |
AzTTP |
10 μl (100 mM) |
|
NU-989L |
AzTTP |
5 x 10 μl (100 mM) |
|
NU-875 |
ara-Adenosine-5′-monophosphate (ara-AMP) |
2 mg |
|
NU-1111S |
ara-Adenosine-5′-triphosphate (ara-ATP) |
50 μl (10 mM) |
|
NU-1111L |
ara-Adenosine-5′-triphosphate (ara-ATP) |
5 x 50 μl (10 mM) |
|
NU-876 |
Acyclovir-5′-monophosphate |
2 mg |
|
NU-877 |
Acyclovir-5′-triphosphate |
2 mg |
|
NU-021-2 |
Ribavirin-5′-monophosphate |
2 mg |
|
NU-1105S |
Ribavirin-triphosphate |
20 μl (10 mM) |
|
NU-1105L |
Ribavirin-triphosphate |
5 x 20 μl (10 mM) |
|
N-DN-8234-100 |
β-L-2′-Deoxythymidine |
100 mg |
|
NU-896S |
6-Aza-UTP |
10 μl (100 mM) |
|
NU-896L |
6-Aza-UTP |
5 x 10 μl (100 mM) |
|
NU-974 |
Tenofovir |
100 mg |
|
NU-975 |
Tenofovir-diphosphate |
1 mg |
|
NU-989S |
AzTTP |
10 μl (100 mM) |
|
NU-989L |
AzTTP |
5 x 10 μl (100 mM) |
|
NU-275S |
Ganciclovir-triphosphate |
10 μl |
|
NU-275L |
Ganciclovir-triphosphate |
5 x 10 μl |
上海金畔生物科技有限公司是Jena bioscience中国一级代理，为用户提供完善的技术与售后服务。如对产品感兴趣欢迎拨打上海金畔生物科技有限公司客服热线021-50837765或登录网址www.jinpanbio.cn了解详细信息。上海金畔生物科技有限公司会更好的协助科研工作者的实验工作，支持全国战“疫”，早日战胜病毒。武汉加油！中国加油！
参考文献：
1] Huang at al. (2011) Effect of reverse transcriptase inhibitors on Line-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochemistry 12:18.
[2] Vaccaro at al. (1999) Mechanism of Inhibition of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase by d4TTP: an Equivalent Incorporation Efficiency Relative to the Natural Substrate dTTP. Antimicrob. Agents Chemother. 44 (1):217.
[3] Jaju at al. (1995) Human immunodeficiency virus type 1 reverse transcriptase. 3′-Azidodeoxythymidine 5′-triphosphate inhibition indicates two-step binding for template-primer. J. Biol. Chem. 270 (17):9740.
[4] Furmann at al. (1979) Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral DNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Triphosphate. J. Virol. 29 (2):154.
[5] Muller at al. (1977) Inhibition of Herpesvirus DNA synthesis by 9-O-D-Arabinofuranosyladenine in cellular and cell-free systems. Ann. N.Y. Acad. Sci. 284:34.
[6] Crotty at al. (2000) The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine 6 (12):1375.
[7] Ray at al. (2009) Metabolism of antiviral nucleosides and nucleotides. In: Antiviral Research: Strategies in antiviral drug discovery (LaFemina). ASM Press.
[8] Simons at al. (2005) Recent Advances in Antiviral Nucleoside and Nucleotide Therapeutics. Current Topics in Medicinal Chemistry 5:1191.