产品基本信息

产品名称：刚果红

CAS：573-58-0

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：696.66

溶剂：水

激发波长(nm)：497

发射波长(nm)：N/A

产品介绍

刚果红（CR）是联苯二重氮-双-1-萘胺-4-磺酸的钠盐。 CR是水溶性的，产生红色胶体溶液。 在组织学中用于染色细胞质和红细胞。淀粉样蛋白沉积以及与其他原纤维沉积物的分化的早期诊断和分类取决于常规的CR组织化学。 该组织学测定法广泛用于体外淀粉样蛋白原纤维的表征。 此外，CR还用于淀粉样蛋白原纤维的荧光检测。 与强光下的CR相比，CR荧光易于执行且效果明显。 尽管未广泛使用，但是用于检测淀粉样蛋白的CR荧光法操作简便，特异性高，灵敏度高，可成功应用于冷冻切片。金畔生物是AAT Bioquest的中国代理商，为您提供优质的刚果红。 

参考文献

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Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway
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Alzheimer’s beta-amyloid: insights into fibril formation and structure from Congo red binding
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Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation
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Pinacyanol as effective probe of fibrillar beta-amyloid peptide: comparative study with Congo Red
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Evidence that supramolecular Congo red is the sole ligation form of this dye for L chain lambda derived amyloid proteins
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Why Congo red binding is specific for amyloid proteins – model studies and a computer analysis approach
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