产品基本信息

产品名称：半柯胺G

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：242.20

溶剂：DMSO

激发波长(nm)：342

发射波长(nm)：N/A

产品介绍

半柯胺G是柯胺G分子的一半，也是大家所熟知的β-淀粉状蛋白沉积物的标签，可以为神经元提供保护，免受由β-淀粉状蛋白25-35和β-淀粉状蛋白40达到一定浓度时引起的神经元死亡。它可以穿过血脑屏障。这种分子在细胞内毒性很小，且与β-淀粉状蛋白40亲和力低。金畔生物是AAT Bioquest的中国代理商，为您提供优质的半柯胺G。 

参考文献

Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer’s Disease with PET
Authors: Solbach C, Uebele M, Reischl G, Machulla HJ.
Journal: Appl Radiat Isot (2005): 591

Mechanism of A beta(1-40) fibril-induced fluorescence of (trans,trans)-1-bromo-2,5-bis(4-hydroxystyryl)benzene (K114)
Authors: LeVine H, 3rd.
Journal: Biochemistry (2005): 15937

Multiple ligand binding sites on A beta(1-40) fibrils
Authors: LeVine H, 3rd.
Journal: Amyloid (2005): 5

Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies
Authors: Ishikawa K, Doh-ura K, Kudo Y, Nishida N, Murakami-Kubo I, Ando Y, Sawada T, Iwaki T.
Journal: J Gen Virol (2004): 1785

Development of a PET/SPECT agent for amyloid imaging in Alzheimer’s disease
Authors: Wang Y, Klunk WE, Debnath ML, Huang GF, Holt DP, Shao L, Mathis CA.
Journal: J Mol Neurosci (2004): 55

In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET
Authors: Verhoeff NP, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S.
Journal: Am J Geriatr Psychiatry (2004): 584

The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
Authors: Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Shao L, Hamilton RL, Ikonomovic MD, DeKosky ST, Mathis CA.
Journal: J Neurosci (2003): 2086